SPECIFICITY OF CELLULAR IMMUNE RESPONSES

Specificity of Cellular Immune Responses

In vitro antigen stimulation of DNA synthesis in lymph node cultures from immunized guinea pigs can be obtained with very low (10(-4) microg/ml) antigen concentrations in the culture fluid. Immunization with low doses of DNP-GPA leads to a cell population capable of being stimulated, on the average, by low concentration of antigen whereas immunization with large antigen doses results in a sensi...

The effect of oral consumption of shark cartilage on the cellular immune responses of cancer patients

Background: Shark cartilage is one of the complementary medicines for cancer patients that inhibits tumor progression by several mechanisms. There is not sufficient evidence on its effects on human immune system thereby we investigated its modulatory effects on some cellular immune response parameters in breast cancer patients. Material and methods: After preparation of shark cartilage powder ...

Cellular Immune Responses in Sheep against Glutathione S-transferase of Fasciola gigantica

Age-Dependent Cellular Immune Responses

The Functional Dissection of an Antigen Molecule: Specificity of Humoral and Cellular Immune Responses to Glucagon

Bovine glucagon, a polypeptide of 29 amino acids, was immunogenic in guinea pigs. The immunologic determinants of glucagon were investigated using isolated tryptic peptides of the hormone. Antibodies from virtually all of more than two dozen animals had specificity primarily for the amino-terminal heptadecapeptide (NM) and showed little or no binding with the carboxy-terminal undeca- and dodeca...